High-Purity PFA Diaphragm Valve (Pneumatic, Weir-type)
Engineered for the most demanding ultra-pure and corrosive fluid handling applications. The CYLEX PFA valve ensures zero contamination, thanks to its seamless PFA construction and diaphragm isolation design. The pneumatic actuator enables automated, reliable switching, while the weir-type mechanism guarantees tight shut-off. Ideal for semiconductor wafer fabrication, biopharmaceutical processes, and high-purity chemical transfer. Choose CYLEX for unmatched reliability and purity.
Model: D-F-ADV5-NC-G216-01A4-FA
Body Size: 60mm
Actuation: Normally Closed
Connector: Weir-type
Port Size: 1″
Actuator Options: Open/Close Only
CYLEX supports small-batch customization, offers discounts for large quantities, fast delivery, and provides guaranteed after-sales service.
Get a quote or inquire for more information about custom processing of PFA Valves .
Processing Cycle:
Material:
Diaphragm: PTFE
Valve body: PFA
Categories :
CYLEX High-Purity PFA Diaphragm Valve (Pneumatic, Weir-type): Ultimate Purity and Corrosion Resistance
Designed for Critical Applications
CYLEX High-Purity PFA Diaphragm Valves are built to meet the stringent requirements of industries where contamination is not an option. Whether you’re managing ultra-pure water (UPW), aggressive acids, solvents, or sensitive bio-pharmaceutical fluids, our valves deliver exceptional performance and long-term reliability.
Key Features and Benefits
● 100% PFA Wetted Surfaces: Guarantees absolute chemical inertness, preventing ion leaching and ensuring fluid stream integrity. Superior to PTFE and other plastics.
● Pneumatic Actuation: Provides fast, automated control for integration into your process control systems. Options for spring-return (fail-safe) and double-acting configurations.
● Weir Design with Reinforced Diaphragm: Our diaphragms utilize PTFE to extend life and ensure a perfect seal every time.
● Zero Dead Leg & Smooth Surface: The valve interior is designed for complete drainage and easy cleaning (CIP/SIP), minimizing particle trapping and bacterial growth.
● Leak-Free Operation: The diaphragm completely isolates the actuator from the media, eliminating any chance of external leakage.
Technical Specifications (D-F-ADV5-NC-G216-01A4-FA):
| Use fluid | Pure water, chemical liquid | ||||||||||
| Fluid temperature | 5~120 °C (Note 1, Note 2) | ||||||||||
| Pressure resistance | 1.0 Mpa | ||||||||||
| Use pressure | A→B: 0~0.5 Mpa B→A: 0~0.5 Mpa | ||||||||||
| Valve seat leakage | 0 cm³/min (Water pressure) | ||||||||||
| Backpressure | 0~0.5Mpa | ||||||||||
| Ambient temperature | 0~60 ℃(With sensor 0〜50 ℃) | ||||||||||
| Frequency | Less than 20 times/minute | ||||||||||
| Diameter | Φ16 | ||||||||||
| Material | Diaphragm: PTFE Valve body: PFA | ||||||||||
Note 1: Please use hydrofluoric acid or chemical liquids containing hydrofluoric acid within the range of 5 to 80°C. | |||||||||||
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Industries We Serve
● Semiconductor: For UPW, CMP slurries, high-purity chemicals like HF, H2SO4.
● Pharmaceutical & Biotech: In WFI systems, buffer solutions, CIP/SIP, and fermentation processes.
● Fine Chemical Processing: Handling highly corrosive reagents and solvents.
● Food & Beverage: For high-purity ingredient dosing and sanitization lines.
Why Choose CYLEX?
● Proven Quality: Rigorous testing ensures every valve meets our high standards.
● Technical Expertise: Our team provides expert support for your specific application needs.
● Competitive Pricing: Direct-to-you pricing without compromising on quality.
● Fast Delivery: Large inventory to ensure fast delivery
Need a Quote or Custom Size? ✉️ Contact CYLEX Today!

Test Type Test Conditions Acceptance Criteria Test Results Burst pressure Hydraulic oil pressure builds up until a leak is detected The burst pressure must be greater than 2 times the rated pressure PASS Pressure envelope 414kPa (60psig)@180°C and 310kPa (45psig)@200°C thermal oil 1 million cycles at 1.5 times rated pressure without external leakage PASS No external leakage Drive cycle test 276kPa (40psig)@180°C and 207kPa (30psig)@200°C thermal oil cycle 500,000 times Functional performance up to 500K cycles without leakage in normally open valves PASS No external or port-to-port leakage <0.050 cc H₂O/hr 276 kPa (40 psig)@180°C and 207 kPa (30 psig)@200°C thermal oil 1 million cycles Functional performance up to 1 million cycles without leakage in normally closed valves PASS No external or port-to-port leakage <0.050 cc H₂O/hr Test Type Test Conditions Acceptance Criteria External medium leakage 552kPa (80psig) CDA Through 1/32″ ID tubing immersed in DI water, no bubbles per minute Port to Port Valve Testing 552kPa (80psig) CDA to valve outlet Less than 4 bubbles per minute through 1/32″ ID tubing immersed in DI water Valve drive Pressure decay 552kPa (80psig) CDA Pressure drop less than 7 kPa (1 psig/min)
Naming Convention

Pneumatic PFA Diaphragm Valve Model Indication and Model Selection

Surface Roughness Specifications & Surface Extractability Specifications

Surface roughness

Surface roughness specification
Surface roughness specification Component Description SEMI F57 0622 Recommended value Ra (µm) Typical test results Ra (µm) Injection molded valve body ≤0.35 ≤0.30 Machine-machined PTFE diaphragm ≤0.35 ≤0.20 Injection molded fitting flow path ≤0.35 ≤0.25 Machine-machined PFA valve body ≤0.60 ≤0.30 Machine-machined PTFE valve body ≤0.60 ≤0.40 Surface extractable specifications
The test liquid used was ultrapure water and the test was carried out at 85°C. The parts were leached after the prescribed rinsing pretreatment. The immersion time was 7 days.
Extractable ionic contamination

Surface extractable ionic contamination
Surface extractable ionic contamination Ion types SEMI F57 0622 Recommended value (µg/m³) Typical product measurement values (ultrapure water 85°C+5°C, 7-day leaching value) (µg/m³) Ammonium ions NH4+ ≤100 <0.1 Bromide ions Br− ≤100 <0.1 Chloride ions Cl− ≤100 <3 Fluoride ions F− ≤20000 <133 Nitrate ions NO3 ≤100 <0.1 Nitrite ions NO2 ≤100 <0.1 Phosphate ions PO42− ≤100 <0.1 Sulfate ions SO42− ≤100 <0.1 Extractable Metal Contamination

Surface extractable metal contaminants
Surface extractable metal contaminants Test items (tcp-ms) SEMI F57 0622 Recommended value (μg/m²) Typical product measurement values (ultrapure water 85°C + 5°C, 7-day leaching value) (μg/m²) Aluminum AI ≤5 <0.2 Arsenic AS ≤2 <0.1 Antimony Sb ≤2 <0.1 Barium Ba ≤15 <0.2 Boron B3 ≤30 <0.5 Cadmium Cd ≤2 <0.01 Calcium Ca ≤10 <0.21 Chromium Cr ≤1 <0.2 Copper Cu ≤10 <0.2 Iron Fe ≤5 <0.2 Lead Pb ≤1 <0.05 Lithium Li ≤2 <0.2 Magnesium Mg ≤2 <0.2 Manganese Mn ≤5 <0.2 Nickel Ni ≤1 <0.2 Potassium K ≤10 <0.5 Sodium Na ≤10 <0.5 Strontium Sr ≤0.5 <0.05 Titanium Ti ≤2 <0.1 Tin Sn ≤2 <0.1 Vanadium V ≤2 <0.01 Zinc Zn ≤5 <0.2
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